The Church of Saint Anne in Krupka is a Roman Catholic filial church located within Libušín's cemetery area, part of Krupka in the Teplice District. Built initially in 1516, this historical monument has undergone various transformations and served different religious communities over the centuries. It stands out for its architectural features and as a cultural heritage site protected since 1964. The church is particularly notable for housing one of the earliest preserved depictions of Martin Luther in the Czech lands.

The origins of the Church of Saint Anne date back to 1516, when it was first constructed. Initially unused, the building later became significant during the Protestant Reformation period in Bohemia, serving as an Evangelical church from 1576 to 1624. During this time, it underwent partial reconstruction in Renaissance style, reflecting the religious and cultural shifts of the era. The sixteenth century was a tumultuous period for Bohemia, marked by religious upheaval as part of the broader Protestant Reformation sweeping across Europe. This context underscores the church's role during its early years as an Evangelical place of worship.

Architecturally, the Church of Saint Anne is distinguished by its elongated pentagonal presbytery with buttresses, adding to its unique character. The façades are simple, adorned only by gabled windows with arches, maintaining a restrained aesthetic typical of Renaissance influences. Inside, the church boasts a two-aisled wooden gallery from the late sixteenth century, decorated with 24 painted panels depicting Old Testament scenes. These elements highlight the artistic and architectural endeavors undertaken during its period as an Evangelical church.

Throughout its history, the Church of Saint Anne has experienced various phases of ownership and administration. After serving as an Evangelical church until 1624, it ceased to be the main city church following repairs in 1684. Over time, particularly in the nineteenth and twentieth centuries, the church underwent several renovations. Today, it is under the spiritual care of the Roman Catholic parish of Krupka, reflecting its transition back to Catholic administration.

The church holds several historical curiosities that enhance its significance. Among these is a sixteenth-century painting depicting Martin Luther, one of his earliest preserved depictions in the Czech lands. Additionally, a Renaissance portal from 1615, constructed by Krupka merchant Georg Klippel, serves as an entrance to the cemetery where the church stands. These features not only add historical depth but also connect the site to broader European cultural and religious narratives.

Currently, the Church of Saint Anne is accessible to visitors during its opening hours from May to September. Despite having been left largely unattended in the early 1990s, leading to some loss of interior furnishings, it remains a site of interest for those exploring Krupka's rich history. The church’s preservation as a cultural monument ensures that its architectural and historical value is maintained for future generations.

Visiting the Church of Saint Anne offers a unique glimpse into the religious and architectural history of the region. Its blend of Renaissance elements and historical significance, including the rare depiction of Martin Luther, makes it a worthwhile destination for those interested in exploring the layers of Bohemian heritage. The church stands as a testament to the dynamic cultural shifts that have shaped this part of Europe over centuries.